Esofagitis necrosante aguda asociada coma diabético hiperosmolar / Acute necrotising oesophagitis associated with hyperosmolar diabetic coma

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Cirugía artroscópica en la inestabilidad anterior traumatica de hombro (tubs). Nuestra experiencia en 30 pacientes / Arthroscopic sugery for anterior traumatic shoulder inestability. Our experience in 30 patients

Introducción: la inestabilidad glenohumeral habitualmente requiere cirugía cuando existe un antecedente traumático previo. Aunque en algunos casos se aboga por un tratamiento conservador, la mayoría de los pacientes precisan de estabilización quirúrgica. Objetivos: presentar nuestra experiencia en la reparación artroscópica en pacientes con luxación recidivante de hombro con componente traumático previo, con especial valoración de factores potencialmente implicados en los casos de reluxación tras la reparación. Métodos: se evaluaron de forma retrospectiva 30 pacientes intervenidos de inestabilidad glenohumeral en los últimos 5 años mediante técnica de Bankart artroscópica, con más de 12 meses de seguimiento posterior a la cirugía. Los pacientes fueron evaluados tras la cirugía mediante escala de ROWE. Se analizaron principalmente el ISIS preoperatorio, el tipo de lesión previa, el número de recidivas, la funcionabilidad y el grado de satisfacción del paciente. Resultados: de los 30 pacientes valorados, la gran mayoría presentaba inestabilidad predominantemente unidireccional, 7 pacientes con lesión de SLAP asociada. De nuestros pacientes, 2 de ellos requirieron nueva cirugía por dolor o inestabilidad. El número de reluxaciones fue dos. Conclusiones: la cirugía artroscópica resuelve gran parte de las inestabilidades unidireccionales y de sus lesiones asociadas con buenos resultados y baja tasa de reluxaciones y satisfacción alta de los pacientes tanto por el confort postoperatorio como por la función final. Es clave la selección adecuada de los pacientes y la reparación depurada de todas las lesiones

Introduction: The glenohumeral instability usually requires surgery when there is a previous history of trauma. Although in some cases it advocates a conservative treatment, most patients require surgical stabilization. Objectives: to present our experience in arthroscopic repair in patients with recurrent shoulder dislocation prior traumatic component, with special consideration of factors potentially involved in cases of redislocation after repair. Methods: We retrospectively evaluated 30 patients undergoing glenohumeral instability over the past 5 years through arthroscopic Bankart technique, with more than 12 months of follow-up after surgery. Patients were evaluated after sur gery by ROWE scale. ISIS preoperatively, type of previous injury, the number of recurrences, the functionality and degree of patient satisfaction was mainly analyzed. Results: Of the 30 patients evaluated, the vast majority had predominantly unidirectional instability, 7 patients with associated SLAP lesion. Of our patients, 2 of them required further surgery for pain and instability. There were 2 cases of redislocations. Conclusions: Arthroscopic surgery solves many of the unidirectional instability and injuries associated with good results and low rate of reluxaciones and high patient satisfaction post operation and final function. The key is proper selection of patients and purified repair of all injuries

Ptosis palpebral: manifestación ocular inusual de la enfermedad de Crohn / Palpebral ptosis, a rare ocular manifestation of Crohn's disease

Caso clínico: Se presenta el caso de una mujer de 18 años con un cuadro de diarrea, dolor abdominal y ptosis palpebral izquierda. La resonancia nuclear magnética cerebral (RMN) y el estudio del líquido cefalorraquídeo fueron normales. La colonoscopia estableció el diagnóstico de enfermedad de Crohn (EC) confirmándose en el estudio histopatológico. La afectación ocular mejoró tras el adecuado tratamiento de la EC. Discusión: La enfermedad inflamatoria intestinal (EII) se asocia a una amplia variedad de manifestaciones extraintestinales, de hecho puede ser considerada como una enfermedad sistémica que afecta predominantemente al tracto gastrointestinal. Las manifestaciones extraintestinales acontecen hasta en una tercera parte de los pacientes afectos de EII. Las complicaciones oculares son infrecuentes, afectando a menos del 10% de los casos, pero en ocasiones comportan una significativa morbilidad, incluyendo la ceguera. La sintomatología ocular puede preceder al diagnóstico de EII. Informamos el primer caso de ptosis palpebral asociado a EC (AU)

Clinical case: An 18 year-old-woman presented with abdominal pain, diarrhea, and ptosis in her left eye. Nuclear magnetic resonance imaging (NMRI) and the study of cerebrospinal fluid detected no abnormalities. Colonoscopy revealed a Crohn's disease (CD) confirmed by histological examination of biopsies. Ocular symptoms improved after appropriate treatment of the underlying CD. Discussion: Inflammatory bowel disease (IBD) is associated with a wide variety of extra-intestinal manifestations, in fact it may be considered a systemic disorder with predominantly gastrointestinal tract manifestations. Extra-intestinal manifestations of inflammatory bowel disease (IBD) occur in one third of patients. Ocular complications are infrequent, occurring in less than 10% of cases, but can be associated with significant morbidity, including blindness. Ocular symptoms may precede a diagnosis of IBD. We report the first case of palpebral ptosis associated with Crohn's disease (AU)

[Palpebral ptosis, a rare ocular manifestation of Crohn's disease]. / Ptosis palpebral: manifestación ocular inusual de la enfermedad de Crohn.

CLINICAL CASE: An 18 year-old-woman presented with abdominal pain, diarrhea, and ptosis in her left eye. Nuclear magnetic resonance imaging (NMRI) and the study of cerebrospinal fluid detected no abnormalities. Colonoscopy revealed a Crohn's disease (CD) confirmed by histological examination of biopsies. Ocular symptoms improved after appropriate treatment of the underlying CD. DISCUSSION: Inflammatory bowel disease (IBD) is associated with a wide variety of extra-intestinal manifestations, in fact it may be considered a systemic disorder with predominantly gastrointestinal tract manifestations. Extra-intestinal manifestations of inflammatory bowel disease (IBD) occur in one third of patients. Ocular complications are infrequent, occurring in less than 10% of cases, but can be associated with significant morbidity, including blindness. Ocular symptoms may precede a diagnosis of IBD. We report the first case of palpebral ptosis associated with Crohn's disease.

Pancreatitis aguda asociada a infección por el virus de Epstein-Barr / Acute pancreatitis associated with Epstein-Barr virus infection

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Varón con dolor agudo en fosa ilíaca izquierda / No disponible

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Efficacy and safety of monotherapy with mycophenolate mofetil in liver transplantation.

AIM: To analyze the efficacy and safety of mycophenolate mofetil (MMF) as monotherapy in liver transplant patients who have adverse effects associated with calcineurin inhibitors (CNIs). PATIENTS AND METHODS: Seventeen patients, 13 men and four women, mean age 62 years, who received a liver transplant between 1998 and 2003 and initial immunosuppressive therapy with CNIs (10 tacrolimus and seven cyclosporine), were converted to monotherapy with MMF due to adverse events associated with CNIs: chronic renal failure in 16 patients (four with diabetes mellitus and seven with hypertension) and neurotoxicity in one patient. The mean time between transplant and starting monotherapy was 32 months (range: 18 to 70) and the mean follow-up time on monotherapy was 20 months (range: 8 to 39). MMF was introduced gradually at the same time as the CNIs were reduced. RESULTS: There was a progressive decrease in creatinine during the initial months. Compared with baseline levels, the differences at 3 and 6 months of monotherapy were significant (P < .001), remaining so throughout the follow-up period. Renal function improved in 15 of 17 patients (88%) and normalized in 10 of 17 (60%). The patient with neurotoxicity due to CNI improved. One patient (6%) had moderate rejection that was corrected after reintroducing tacrolimus. In two patients it was necessary to suspend MMF, one due to gastrointestinal intolerance and the other due to severe myelotoxicity and Pneumocystis jiroveci infection. Other, minor adverse events were corrected by adjusting the dose: one herpes zoster, two diarrhea, and two anemia. CONCLUSIONS: Monotherapy with MMF efficiently and safely corrected renal dysfunction associated with CNIs, with few side effects and a low incidence of rejection.